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dposada June 28, 2022

Scalable single-cell phylogenies

Nice collaboration with Luay Nakhleh and Hamim Zafar labs on scalable single-cell phylogenetic inference:

Phylovar: toward scalable phylogeny-aware inference of single-nucleotide variations from single-c…

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dposada - 10 posts papers publications, single-cell, somatic

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mini-review on single-cell DNA variant callers

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phylogenetic origins of relapse using single-cell data

Our phylogenetic analysis of single cells exposes how, where and when malignant cells survive treatment in a personalized manner in…

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mtDNA single-cell paper

In CRC, mtDNA heteroplasmy mainly arises from differences among cells, but in some cases, the ancestral tumor cell can host…

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Understanding SARS-CoV-2 transmission

Together with colleagues at a local hospital, here we show that is not easy to figure out with just genomics…

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Recent Posts

  • Scalable single-cell phylogenies June 28, 2022
  • mini-review on single-cell DNA variant callers June 20, 2022
  • phylogenetic origins of relapse using single-cell data June 13, 2022
  • mtDNA single-cell paper February 21, 2022
  • Understanding SARS-CoV-2 transmission February 7, 2022

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    David Posada Follow

    A computational evolutionary biologist lately interested in cancer evolution.

    dposada_
    Retweet on Twitter David Posada Retweeted
    yosoykit Kit Curtius @yosoykit ·
    1 Aug

    We're hiring! Get in touch about Postdoc and Data Analyst positions that include math modeling and risk prediction using clinical, epi, and molecular data. Our dynamic team aims to catch and thwart cancer evolution sooner. #earlydetection #mathonco

    Reply on Twitter 1554142240074739714 Retweet on Twitter 1554142240074739714 26 Like on Twitter 1554142240074739714 34 Twitter 1554142240074739714
    Retweet on Twitter David Posada Retweeted
    andreasottoriva Andrea Sottoriva @andreasottoriva ·
    20 Jul

    New #PhDposition(s) in #DataScience applied to #biomedical research thanks to a new exciting collaboration between @Sissaschool and @humantechnopole. Join us! [deadline 31/08] https://www.sissa.it/bandi/selection-conferment-three-phd-fellowships-theoretical-and-scientific-data-science-financed. #SingleCell #imaging #antibiotics #MachineLearning #ArtificialIntelligence

    Reply on Twitter 1549664716750045189 Retweet on Twitter 1549664716750045189 33 Like on Twitter 1549664716750045189 37 Twitter 1549664716750045189
    dposada_ David Posada @dposada_ ·
    28 Jun

    Nice collaboration with @NakhlehRice and @Quasarzafar labs on scalable single-cell phylogenetic inference: https://doi.org/10.1093/bioinformatics/btac254

    Reply on Twitter 1541702269086957572 Retweet on Twitter 1541702269086957572 2 Like on Twitter 1541702269086957572 7 Twitter 1541702269086957572
    dposada_ David Posada @dposada_ ·
    20 Jun

    A simple review on scDNA-seq variant callers: https://doi.org/10.1016/j.csbj.2022.06.013

    Reply on Twitter 1538788198884728832 Retweet on Twitter 1538788198884728832 4 Like on Twitter 1538788198884728832 18 Twitter 1538788198884728832
    dposada_ David Posada @dposada_ ·
    13 Jun

    Here we show how single-cell cancer genomics can help to understand how a liver relapse took place in a mCRC patient. Great collaborative work with @CD68PHD2, @JMFAlves et al:
    https://doi.org/10.1016/j.canlet.2022.215767

    Reply on Twitter 1536250686555492352 Retweet on Twitter 1536250686555492352 9 Like on Twitter 1536250686555492352 29 Twitter 1536250686555492352
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