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papers

New paper: Detecting changes in the evolutionary rate of cell lineages

Check our new paper on changes in the evolutionary rate among somatic lineages! https://cell.com/cell-genomics/fulltext/S2666-979X(23)00177-5… Here, we developed a novel phylogenetic…

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SIEVE: joint inference of single‑nucleotide
variants and cell phylogeny from single‑cell
DNA sequencing data

A very nice collaboration with the Szczurek and Beerenwinkel labs under the Computational ONcology TRaining Alliance Innovative Training (CONTRA) Network.…

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Genomic characterization of circulating tumor cells

Today out in Genomics! We found substantial differences in the mutational loads of CTC pools obtained using different CTC-capture methods.…

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On the root of eukaryotes

We started this collaboration with the Katz lab and today is finally out!  Using phylogenomics, we propose that the eukaryote…

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Scalable single-cell phylogenies

Nice collaboration with Luay Nakhleh and Hamim Zafar labs on scalable single-cell phylogenetic inference: Phylovar: toward scalable phylogeny-aware inference of…

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phylogenetic origins of relapse using single-cell data

Our phylogenetic analysis of single cells exposes how, where and when malignant cells survive treatment in a personalized manner in…

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mtDNA single-cell paper

In CRC, mtDNA heteroplasmy mainly arises from differences among cells, but in some cases, the ancestral tumor cell can host…

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Understanding SARS-CoV-2 transmission

Together with colleagues at a local hospital, here we show that is not easy to figure out with just genomics…

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Recent Posts

  • New paper: Detecting changes in the evolutionary rate of cell lineages September 14, 2023
  • We are hiring a lab tech! May 31, 2023
  • SIEVE: joint inference of single‑nucleotide
    variants and cell phylogeny from single‑cell
    DNA sequencing data
    December 2, 2022
  • Genomic characterization of circulating tumor cells October 11, 2022
  • On the root of eukaryotes August 11, 2022

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    October 2023
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    David Posada Follow

    A computational evolutionary biologist lately interested in cancer evolution.

    dposada_
    dposada_ David Posada @dposada_ ·
    13 Sep

    Check our new paper on changes in the evolutionary rate among somatic lineages!

    A nice collaboration with Nico Borgsmüller, @linkmonica, Jack Kuipers, and Niko Beerenwinkle

    Reply on Twitter 1701977917599703117 Retweet on Twitter 1701977917599703117 15 Like on Twitter 1701977917599703117 61 Twitter 1701977917599703117
    Retweet on Twitter David Posada Retweeted
    alexiscompbio Alexis Stamatakis @alexiscompbio ·
    2 Aug

    We have just opened 3 PhD positions in the new, Biodiversity Computing Research group I am setting up in Crete https://www.biocomp.gr/ application deadline is August 31, to apply: https://euraxess.ec.europa.eu/jobs/131920 #postdoc #research

    Reply on Twitter 1686680279639801856 Retweet on Twitter 1686680279639801856 147 Like on Twitter 1686680279639801856 198 Twitter 1686680279639801856
    dposada_ David Posada @dposada_ ·
    31 May

    Buscamos un técnico de laboratorio a tiempo completo. Oferta 1023-109593 (en español e inglés) en https://secretaria.uvigo.gal/uv/web/convocatoria/public/show/1150. Abierta hasta el 6 de junio. ¡Trabajemos juntos!

    Reply on Twitter 1663800381833445376 Retweet on Twitter 1663800381833445376 12 Like on Twitter 1663800381833445376 10 Twitter 1663800381833445376
    dposada_ David Posada @dposada_ ·
    31 May

    We are looking for a full-time laboratory technician. Offer 1023-109593 (in Spanish and English) at https://secretaria.uvigo.gal/uv/web/convocatoria/public/show/1150. Open until June 6. Let's work together!

    Reply on Twitter 1663800335666667520 Retweet on Twitter 1663800335666667520 2 Like on Twitter 1663800335666667520 2 Twitter 1663800335666667520
    Retweet on Twitter David Posada Retweeted
    traingene Todd J Treangen @traingene ·
    27 Apr

    Down to the final 36 hours to register for CINEMA, a free 6 day workshop on environmental and clinical microbiome analysis 🦠💻 🔬

    Registration deadline is tomorrow April 28th. Only a couple spots remain, register today if you are interested in attending https://forms.gle/Aw5N6pGyHWJHJE2Q9

    Reply on Twitter 1651612466151841792 Retweet on Twitter 1651612466151841792 6 Like on Twitter 1651612466151841792 7 Twitter 1651612466151841792
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