🔬 Our new study in Genomics, Proteomics, and Bioinformatics shows that we can recover cell phylogenies from scRNA-seq data and…
Continue ReadingNew paper in Genome Medicine
🧬 New in Genome Medicine! Deep genomic analysis of relapsed colorectal cancer liver metastases reveals patient-specific evolutionary trajectories and multiple…
Continue ReadingNew paper on CTC genomics as biomarker
Excited to share our latest open-access publication in Cellular Oncology:“Genomic diversity and BCL9L mutational status in circulating tumor cells predict…
Continue ReadingCrykey: New Tool for Detecting SARS-CoV-2 Mutations in Wastewater
We have collaborated on a new paper on Nature Communications introducing Crykey, for large-scale detection of cryptic mutations in wastewater…
Continue ReadingNew paper: Detecting changes in the evolutionary rate of cell lineages
Check our new paper on changes in the evolutionary rate among somatic lineages! https://cell.com/cell-genomics/fulltext/S2666-979X(23)00177-5… Here, we developed a novel phylogenetic…
Continue ReadingSIEVE: joint inference of single‑nucleotide
variants and cell phylogeny from single‑cell
DNA sequencing data
A very nice collaboration with the Szczurek and Beerenwinkel labs under the Computational ONcology TRaining Alliance Innovative Training (CONTRA) Network.…
Continue ReadingGenomic characterization of circulating tumor cells
Today out in Genomics! We found substantial differences in the mutational loads of CTC pools obtained using different CTC-capture methods.…
Continue ReadingOn the root of eukaryotes
We started this collaboration with the Katz lab and today is finally out! Â Using phylogenomics, we propose that the eukaryote…
Continue ReadingScalable single-cell phylogenies
Nice collaboration with Luay Nakhleh and Hamim Zafar labs on scalable single-cell phylogenetic inference: Phylovar: toward scalable phylogeny-aware inference of…
Continue Readingphylogenetic origins of relapse using single-cell data
Our phylogenetic analysis of single cells exposes how, where and when malignant cells survive treatment in a personalized manner in…
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